AICAR Reconstitution Calculator
Enter the amount you want to measure. The vial buttons will highlight which vial strengths create cleaner syringe-unit measurements.
What amount do you need?
Type the target amount, then choose mg or mcg. Example: 2mg or 500mcg.
Syringe size:
Possible vial strengths:
Best Match
Good Match
Usable
Harder to Measure
Example AICAR Titration Schedule
| Research Context (as described) | Timeline | Dose | Notes |
|---|---|---|---|
| Skeletal muscle research (6.5-week protocol) | Weeks 1–4 | 500 mg/kg body weight (daily injection) | Front-loaded “high dose” phase |
| Skeletal muscle research (6.5-week protocol) | Weeks 4–6.5 | Lower dose (daily injection) | Article notes the dose is reduced, but does not specify the exact amount |
| Metabolic syndrome / type 2 diabetes example | Up to 13 weeks | 1 mg/kg per day (injections) | Presented as an example tied to blood sugar homeostasis research |
| Fat tissue metabolism example | 4–8 weeks | 0.5–1.0 g/kg per day (intraperitoneal injection) | Article cites 0.7 g/kg as an “optimal” value for this context |
Possible vial strengths:
What Is It?
AICAR
AMPK activator research compound.
Bacteriostatic Water
Sterile water containing a bacteriostatic preservative, commonly used when preparing multi-use research vials.
How To Mix AICAR
1
CleanUse alcohol swabs to clean the tops of both vials.
2
Draw BAC WaterDraw the selected amount of bacteriostatic water.
3
Inject SlowlyAdd the liquid slowly down the side of the vial.
4
Swirl GentlyDo not shake. Swirl gently until dissolved.
5
Store ProperlyStore as directed and protect from heat and light.
Best Practices & Common Mistakes
Best Practices
- Use sterile technique.
- Protect from light and heat.
- Store refrigerated when appropriate.
- Use clean syringe-unit math before measuring.
Common Mistakes
- Confusing milligrams with milliliters.
- Choosing an option with awkward decimal units.
- Using too little liquid for very small measurements.
- Shaking the vial aggressively.
AICAR Storage & Handling
Lyophilized Powder: −20°C (−4°F) for long-term storage (up to 24 months). Refrigeration 2–8°C (36–46°F) for short-term use (up to ~3 months). Original sealed vial in the freezer is safest.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Frequently Asked Questions
AICAR, also called acadesine or AICA-riboside, is a research compound used to study AMPK signaling and cellular energy metabolism. It is often marketed beside peptides, but it is not a peptide; it is a nucleoside-related compound that can be converted inside cells into ZMP.
No. AICAR is a research compound, while A1C or HbA1c is a blood test used to estimate average blood sugar over about three months. If someone searches “normal AIC,” they usually mean A1C, not AICAR.
AICAR is commonly called a “peptide” online because it appears on peptide-research websites, but chemically that label is wrong. For calculator users, the important point is that AICAR is handled as a research compound with concentration math, not as a normal amino-acid peptide chain.
AICAR calculator math starts with the vial amount and final liquid volume. For example, a 50 mg AICAR vial brought to 8 mL final volume gives 6.25 mg/mL; a 2 mg research amount would equal 0.32 mL, or 32 units on a U-100 syringe.
The main safety issue is that AICAR affects energy-signaling biology, and not all effects are simply “AMPK activation.” It also has anti-doping relevance: AICAR is listed as a prohibited metabolic modulator in sport, so endurance and “exercise mimetic” claims should be treated carefully.
Practical takeaway: If your real goal is weight or metabolic health, the most useful next step is discussing approved treatment options with a clinician rather than relying on an unapproved compound.
Important: This tool is for informational and research-reference purposes only. Not intended for human or veterinary use.