GDF11 Reconstitution Calculator
Enter the amount you want to measure. The vial buttons will highlight which vial strengths create cleaner syringe-unit measurements.
What amount do you need?
Type the target amount, then choose mg or mcg. Example: 2mg or 500mcg.
Work the dose out from body weight
Example GDF11 Titration Schedule
| Parameter | Details |
|---|---|
| Mouse dose | 0.1 mg/kg/day IP |
| Human dose | None established |
The 'rejuvenation' premise has been substantially walked back: follow-up studies failed to reproduce the decline-with-age, found GDF11 pro-atrophic at high levels (SMAD3 → MuRF1/atrogin-1), and a 2026 human study associated higher GDF11 with sarcopenia. Mouse data only; no human dosing exists.
What Is It?
GDF11
Growth differentiation factor 11, TGF-β family.
Bacteriostatic Water
Sterile water containing a bacteriostatic preservative, commonly used when preparing multi-use research vials.
How To Mix GDF11
Use alcohol swabs to clean the tops of both vials.
Draw the selected amount of bacteriostatic water.
Add the liquid slowly down the side of the vial.
Do not shake. Swirl gently until dissolved.
Store as directed and protect from heat and light.
Best Practices & Common Mistakes
Best Practices
- Use sterile technique.
- Protect from light and heat.
- Store refrigerated when appropriate.
- Use clean syringe-unit math before measuring.
Common Mistakes
- Confusing milligrams with milliliters.
- Choosing an option with awkward decimal units.
- Using too little liquid for very small measurements.
- Shaking the vial aggressively.
GDF11 Storage & Handling
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.