HMG Reconstitution Calculator
Enter the amount you want to measure. The vial buttons will highlight which vial strengths create cleaner syringe-unit measurements.
What amount do you need?
Type the target amount, then choose mg or mcg. Example: 2mg or 500mcg.
Syringe size:
Possible vial strengths:
Best Match
Good Match
Usable
Harder to Measure
Example HMG Titration Schedule
| Parameter | Details |
|---|---|
| Typical Dosage (Female) | 75–225 IU/day (starting dose commonly 75–150 IU) [7†L28-L29]. Max daily: 450 IU (treatment >20 days not recommended) [9†L42-L43]. |
| Typical Dosage (Male) | For spermatogenesis: 75–150 IU three times weekly [7†L47-L48]. |
| Route | Subcutaneous (SC) or Intramuscular (IM) [4†L44-L45][5†L5-L6]. |
| Frequency (Female) | Once daily, typically for 5–12 days (adjusted based on response) [7†L30-L31]. |
| Frequency (Male) | Combined therapy with hCG for at least 4 months [5†L20-L21]. |
| Cycle Length (Female) | Treatment until adequate ovarian follicular development (then trigger with hCG 5,000–10,000 IU) [4†L37-L38]. |
| Half‑life (sc) | 51 hours [4†L20-L22]. |
Possible vial strengths:
75IU, 150IU
What Is It?
HMG
Human menopausal gonadotropin reference compound.
Bacteriostatic Water
Sterile water containing a bacteriostatic preservative, commonly used when preparing multi-use research vials.
How To Mix HMG
1
CleanUse alcohol swabs to clean the tops of both vials.
2
Draw BAC WaterDraw the selected amount of bacteriostatic water.
3
Inject SlowlyAdd the liquid slowly down the side of the vial.
4
Swirl GentlyDo not shake. Swirl gently until dissolved.
5
Store ProperlyStore as directed and protect from heat and light.
Best Practices & Common Mistakes
Best Practices
- Use sterile technique.
- Protect from light and heat.
- Store refrigerated when appropriate.
- Use clean syringe-unit math before measuring.
Common Mistakes
- Confusing milligrams with milliliters.
- Choosing an option with awkward decimal units.
- Using too little liquid for very small measurements.
- Shaking the vial aggressively.
HMG Storage & Handling
Lyophilized Powder: −20°C (−4°F) for long-term storage (up to 24 months). Refrigeration 2–8°C (36–46°F) for short-term use (up to ~3 months). Original sealed vial in the freezer is safest.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Reconstituted Solution: 2–8°C (36–46°F), use within ~7–14 days. Keep sealed, avoid light, and do not repeat freeze-thaw cycles.
Frequently Asked Questions
On this page, HMG means human menopausal gonadotropin, also known as menotropins. The calculator should treat it as a hormone preparation measured in IU, not as a general abbreviation with multiple meanings.
Not exactly. HMG is better described as a gonadotropin hormone preparation with FSH and LH activity, so the useful calculator unit is usually IU/mL. Calling it a peptide can confuse the concentration format.
No. HMG-CoA reductase is a different biochemical term connected with cholesterol metabolism and statins. It should not be mixed with HMG reconstitution math for human menopausal gonadotropin.
The calculator needs the total IU listed on the vial and the final liquid volume in mL. If the label separates FSH and LH activity, those values should be read from the product label or batch document rather than guessed.
Only as concentration math. The calculator can show IU/mL after reconstitution, but it should not provide injection technique, frequency, treatment use, fertility protocols, or personal dosing advice.
Practical takeaway: If your real goal is weight or metabolic health, the most useful next step is discussing approved treatment options with a clinician rather than relying on an unapproved compound.
Important: This tool is for informational and research-reference purposes only. Not intended for human or veterinary use.